Protip SAS is an SME based in Strasbourg, France. With over 10 years of expertise in developing and testing medical prostheses and implants based on porous titanium, its main focus lies in otorhinolaryngology applications. The company has established partnerships with several academic establishments, including the University Hospitals of Strasbourg as well as INSERM, one of IMMODGEL´s scientific partners.
The company holds unique expertise in manufacturing complex form factors based on medical grade titanium microspheres and is able to produce numerous types of implants varying in final form, porosity and composition. Protip patented an innovative procedure that allows the manufactured biomaterial to be implanted permanently, even in a septic environment.
Furthermore, Protip has produced the artificial larynx “ENTgral” which is currently under clinical trials and has recently introduced a thyroplasty prosthesis for use in laryngeal surgery onto the market. Moreover, a phonatory implant is currently in its final design phase.
Role in IMMODGEL
As IMMODGEL´s Scientific Coordinator, Protip takes over the overall scientific management of the project.
Moreover, it applies its vast expertise in biomaterials used in otorhynolaryngological devices to design and produce porous titanium implants and to optimise the hydrogel. It will test and characterise the cell encapsulation system as well as the macrophages in both the short- and long-term after encapsulation. It is furthermore responsible for the development of cytokine release within the design and the optimisation of the foreign body response on-a-chip system.
Making use of its partnerships with hospitals, it is in charge of clinical sample procurement from artificial larynx trials and in vivo testing of the immunomodulatory hydrogel necessary for the development of commercial products.